Oral Tablet
- Insurance90-day supply
- $10+
- Cost Plus DrugsLive90-day supply
- $8.10Lowest listed
- GoodRx90-day cash pay
- $18-25
- HRT Club90-day cash pay
- $30
Medication pricing
Clearer costs. More control.
Compare approximate 90-day costs for common menopause prescriptions across insurance and cash-pay options.
Compare prescriptions
Start with the medication type.
Prices vary by dose, pharmacy, location, and insurance plan. Use these estimates as a starting point, then confirm your exact price with the pharmacy.
Estradiol (Systemic) costs
Systemic estradiol is delivered throughout your body to treat hot flashes, night sweats, and other vasomotor symptoms of menopause.
Cost Plus updated
September 16, 2026 at 5:48 PM UTC
| Delivery method | Insurance90-day supply | Cost Plus DrugsLive90-day supply | GoodRx90-day cash pay | HRT Club90-day cash pay |
|---|---|---|---|---|
| Oral Tablet | $10+ | $8.10Lowest listed | $18-25 | $30 |
| Twice-Weekly Patch | $10+Lowest listed | $133.48 | $60-180 | $144 |
| Once Weekly Patch | $10+Lowest listed | $95.36 | $150 | Not listed |
| Daily Gel Packet | $10-50Lowest listed | Not listed | Not listed | $105 |
| Gel Pump (Estragel) | Varies | Not listed | $170-250 | $90Lowest listed |
| Mist (Evamist) | Varies | Not listed | $225Lowest listed | Not listed |
These are pharmacy prices, not charges from MyMenopauseRx. Your specialist will send your prescription to the pharmacy you choose.
Your virtual visit
Care costs and medication costs are separate.
We accept most major commercial health insurance plans. You pay your copay, coinsurance, or deductible for the visit, while your pharmacy handles the prescription cost.
- Personalized care plan
- Your choice of pharmacy
- FSA/HSA eligible
- $99 self-pay visits
Meet with your specialist
Discuss your symptoms, health history, and treatment preferences.
Choose a treatment plan
Your specialist explains appropriate options and sends your prescription.
Fill it where you prefer
Compare prices and use the pharmacy that works best for you.
Pricing notes
Cost Plus Drugs prices come from its public API and include its standard markup, pharmacy fee, and shipping. GoodRx and HRT Club prices are approximate ranges based on publicly available data. Insurance costs depend on your plan. Always confirm pricing with your pharmacy before filling a prescription.